Basic Information
ID: ALA4405867
Type: Binding
Description: Inhibition of hexahistidine-SUMO tagged Mycobacterium tuberculosis InhA expressed in Escherichia coli BL21(DE3) at 0.1 mM preincubated for 10 mins with NADH before addition of 2-trans-octanoyl-CoA as substrate and measured after 20 mins by NADH oxidation detection based colorimetric assay relative to control
Format: BAO_0000019
Organism: Mycobacterium tuberculosis
Target: Enoyl-[acyl-carrier-protein] reductase(ALA1849)
Document: ALA4402593
Inhibition of hexahistidine-SUMO tagged Mycobacterium tuberculosis InhA expressed in Escherichia coli BL21(DE3) at 0.1 mM preincubated for 10 mins with NADH before addition of 2-trans-octanoyl-CoA as substrate and measured after 20 mins by NADH oxidation detection based colorimetric assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4405867
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 366.90 | 4.12 | 4.12 |
| 371.34 | 3.82 | 3.82 |
| 318.42 | 3.16 | 3.16 |
| 356.37 | 3.58 | 3.58 |
| 328.31 | 3.51 | 3.51 |
| 327.33 | 4.12 | 4.12 |
| 357.35 | 4.13 | 4.13 |
| 398.41 | 3.75 | 3.75 |
| 342.34 | 3.70 | 3.70 |
| 370.40 | 3.84 | 3.84 |
| 334.36 | 2.35 | 2.35 |
| 356.37 | 3.58 | 3.58 |
| 318.44 | 3.24 | 3.24 |
| 382.41 | 3.76 | 3.76 |
| 302.36 | 2.69 | 2.69 |
| 385.36 | 3.90 | 3.90 |
| 340.45 | 3.28 | 3.28 |
| 442.46 | 5.47 | 5.47 |
| 399.39 | 3.83 | 3.83 |
| 370.35 | 3.22 | 3.22 |
| 350.44 | 3.61 | 3.61 |