Basic Information
ID: ALA4406071
Type: Functional
Description: Agonist activity at human Gi/o-coupled D3 receptor expressed in HEK293T cells assessed as inhibition of isoproterenol-induced cAMP accumulation preincubated for 15 mins followed by isoproterenol addition by Glosensor-based luminescence assay
Format: BAO_0000219
Organism: Homo sapiens
Target: Dopamine D3 receptor(ALA234)
Document: ALA4402598
Agonist activity at human Gi/o-coupled D3 receptor expressed in HEK293T cells assessed as inhibition of isoproterenol-induced cAMP accumulation preincubated for 15 mins followed by isoproterenol addition by Glosensor-based luminescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4406071
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 176.22 | 1.37 | 1.37 |
| 153.18 | 0.60 | 0.60 |
| 219.33 | 2.00 | 2.00 |
| 508.92 | 6.50 | 6.50 |
| 546.97 | 7.08 | 7.08 |
| 519.94 | 7.17 | 7.17 |
| 526.10 | 5.92 | 5.92 |
| 546.97 | 7.08 | 7.08 |
| 519.94 | 7.17 | 7.17 |
| 508.92 | 6.50 | 6.50 |
| 526.10 | 5.92 | 5.92 |