Basic Information
ID: ALA4406078
Type: Functional
Description: Agonist activity at human 5HT2C receptor stably expressed in HEK293 cells co-expressing Gq assessed as induction of calcium mobilization measured at 1 sec interval for 60 secs by Fluo-4 calcium dye based FLIPR assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Serotonin 2c (5-HT2c) receptor(ALA225)
Document: ALA4402598
Agonist activity at human 5HT2C receptor stably expressed in HEK293 cells co-expressing Gq assessed as induction of calcium mobilization measured at 1 sec interval for 60 secs by Fluo-4 calcium dye based FLIPR assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4406078
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 176.22 | 1.37 | 1.37 |
| 153.18 | 0.60 | 0.60 |
| 219.33 | 2.00 | 2.00 |
| 546.97 | 7.08 | 7.08 |
| 519.94 | 7.17 | 7.17 |
| 508.92 | 6.50 | 6.50 |