Basic Information
ID: ALA4406420
Type: Binding
Description: Ratio of IC50 for inhibition of CYP4Z1 (unknown origin) in human HepG2 cell membranes transduced with lentiviral vector using luciferin-benzyl ether as substrate incubated for 5 mins followed by NADPH addition and measured after 20 mins to IC50 for inhibition of CYP4Z1 (unknown origin) in human HepG2 cell membranes transduced with lentiviral vector using luciferin-benzyl ether as substrate preincubated with NADPH for 30 mins followed by substrate addition and measured after 10 mins by P450-glo luciferase based luminescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4406420
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 134.14 | 0.15 | 0.15 |
| 332.45 | 3.96 | 3.96 |
| 248.29 | 1.62 | 1.62 |
| 246.36 | 3.34 | 3.34 |
| 274.41 | 4.12 | 4.12 |
| 302.47 | 4.90 | 4.90 |
| 276.34 | 2.40 | 2.40 |
| 218.30 | 2.56 | 2.56 |
| 190.25 | 1.77 | 1.77 |
| 304.39 | 3.18 | 3.18 |