Basic Information
ID: ALA4406426
Type: ADME
Description: Inhibition of CYP4F8 (unknown origin) in human HepG2 cell membranes transduced with lentiviral vector at 30 uM using Luc-BE as substrate preincubated with NADPH for 30 mins followed by substrate addition and measured after 10 mins by P450-glo luciferase based luminescence assay
Organism: Homo sapiens
Cell type: HepG2
Activity Charts
Bioactivity
Activity Types for Assay ALA4406426
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 332.45 | 3.96 | 3.96 |
| 248.29 | 1.62 | 1.62 |
| 276.34 | 2.40 | 2.40 |
| 304.39 | 3.18 | 3.18 |