Basic Information
ID: ALA4406525
Type: ADME
Description: Antagonist activity at human PK1-tagged Gq-coupled ADRA1B expressed in CHOK1 cells assessed as inhibition of 7alpha,25-ihydroxycholesterol-induced beta-arrestin recruitment at 10 uM measured after 120 mins by beta-galactosidase based PathHunter assay relative to control
Format: BAO_0000219
Organism: Homo sapiens
Target: Alpha-1b adrenergic receptor(ALA232)
Document: ALA4402608
Antagonist activity at human PK1-tagged Gq-coupled ADRA1B expressed in CHOK1 cells assessed as inhibition of 7alpha,25-ihydroxycholesterol-induced beta-arrestin recruitment at 10 uM measured after 120 mins by beta-galactosidase based PathHunter assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4406525
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 379.46 | 3.01 | 3.01 |