Basic Information
ID: ALA4406753
Type: Binding
Description: Selectivity index, ratio of IC50 for inhibition of human ALK5 using casein as substrate in presence of 10 uM [gamma33P] ATP by radioactive assay to IC50 for inhibition of human ALK3 using casein as substrate in presence of 10 uM [gamma33P] ATP by radioactive assay
Format: BAO_0000019
Organism: Homo sapiens
Target: Unchecked(ALA612545)
Document: ALA4402613
Selectivity index, ratio of IC50 for inhibition of human ALK5 using casein as substrate in presence of 10 uM [gamma33P] ATP by radioactive assay to IC50 for inhibition of human ALK3 using casein as substrate in presence of 10 uM [gamma33P] ATP by radioactive assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4406753
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 406.49 | 4.02 | 4.02 |
| 405.50 | 3.85 | 3.85 |
| 419.53 | 4.16 | 4.16 |
| 436.94 | 3.89 | 3.89 |
| 462.57 | 4.50 | 4.50 |
| 416.53 | 3.38 | 3.38 |
| 420.49 | 3.38 | 3.38 |
| 408.53 | 3.30 | 3.30 |
| 402.50 | 3.24 | 3.24 |
| 474.61 | 4.37 | 4.37 |
| 419.53 | 4.16 | 4.16 |
| 474.61 | 4.37 | 4.37 |
| 462.57 | 4.50 | 4.50 |
| 408.53 | 3.30 | 3.30 |
| 402.50 | 3.24 | 3.24 |
| 432.52 | 3.25 | 3.25 |
| 390.46 | 3.37 | 3.37 |
| 372.47 | 3.23 | 3.23 |
| 434.52 | 3.72 | 3.72 |
| 384.48 | 3.38 | 3.38 |