Basic Information
ID: ALA4406759
Type: ADME
Description: Inhibition of ALK5 (unknown origin) expressed in HEK293 cells transfected with CAGA-luciferase and Renilla luciferase reporter measured after 24 hrs by dual luciferase reporter assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4406759
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 436.94 | 3.89 | 3.89 |
| 462.57 | 4.50 | 4.50 |
| 446.55 | 3.59 | 3.59 |
| 416.53 | 3.50 | 3.50 |
| 416.53 | 3.38 | 3.38 |
| 420.49 | 3.38 | 3.38 |
| 408.53 | 3.30 | 3.30 |
| 402.50 | 3.24 | 3.24 |
| 430.55 | 3.84 | 3.84 |
| 474.61 | 4.37 | 4.37 |
| 474.61 | 4.37 | 4.37 |
| 402.50 | 3.24 | 3.24 |
| 408.53 | 3.30 | 3.30 |
| 462.57 | 4.50 | 4.50 |
| 408.53 | 3.30 | 3.30 |
| 402.50 | 3.24 | 3.24 |
| 432.52 | 3.25 | 3.25 |
| 390.46 | 3.37 | 3.37 |
| 372.47 | 3.23 | 3.23 |
| 434.52 | 3.72 | 3.72 |
| 384.48 | 3.38 | 3.38 |