Basic Information
ID: ALA4406779
Type: ADME
Description: Inhibition of CYP2B6 in human liver microsomes using bupropion as substrate incubated for 40 mins in presence of NADPH by LC-MS/MS analysis
Format: BAO_0000251
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsomes
Target: Cytochrome P450 2B6(ALA4729)
Document: ALA4402613
Inhibition of CYP2B6 in human liver microsomes using bupropion as substrate incubated for 40 mins in presence of NADPH by LC-MS/MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4406779
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 462.57 | 4.50 | 4.50 |
| 462.57 | 4.50 | 4.50 |
| 434.52 | 3.72 | 3.72 |