Basic Information
ID: ALA4406784
Type: ADME
Description: Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate incubated for 40 mins in presence of NADPH by LC-MS/MS analysis
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsomes
Activity Charts
Bioactivity
Activity Types for Assay ALA4406784
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 462.57 | 4.50 | 4.50 |
| 462.57 | 4.50 | 4.50 |
| 434.52 | 3.72 | 3.72 |