Basic Information
ID: ALA4406959
Type: Functional
Description: Anti-necroptotic activity in human HT-29 cells assessed as inhibition of NFalpha/SM-164/Z-VAD-fmk-induced necroptosis measured after 12 hrs by celltiter-glo luminescent cell viability assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HT-29
Target: HT-29(ALA384)
Document: ALA4406794
Anti-necroptotic activity in human HT-29 cells assessed as inhibition of NFalpha/SM-164/Z-VAD-fmk-induced necroptosis measured after 12 hrs by celltiter-glo luminescent cell viability assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4406959
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 554.53 | 6.65 | 6.65 |
| 597.51 | 7.80 | 7.80 |
| 547.51 | 6.92 | 6.92 |
| 543.54 | 7.17 | 7.17 |
| 545.51 | 6.66 | 6.66 |
| 476.53 | 6.53 | 6.53 |
| 475.55 | 6.07 | 6.07 |
| 626.68 | 8.99 | 8.99 |
| 501.51 | 7.21 | 7.21 |
| 534.57 | 6.40 | 6.40 |
| 620.58 | 8.05 | 8.05 |
| 491.54 | 5.77 | 5.77 |
| 541.40 | 6.98 | 6.98 |
| 505.53 | 5.49 | 5.49 |
| 514.58 | 6.25 | 6.25 |
| 542.51 | 6.65 | 6.65 |
| 486.53 | 5.63 | 5.63 |
| 590.56 | 7.55 | 7.55 |
| 462.51 | 5.15 | 5.15 |
| 529.52 | 6.78 | 6.78 |
| 551.54 | 6.40 | 6.40 |
| 563.96 | 7.43 | 7.43 |
| 529.52 | 6.78 | 6.78 |
| 477.52 | 5.46 | 5.46 |
| 504.54 | 6.42 | 6.42 |
| 489.57 | 6.37 | 6.37 |
| 547.51 | 6.92 | 6.92 |
| 477.52 | 5.92 | 5.92 |
| 540.50 | 6.72 | 6.72 |
| 555.55 | 7.27 | 7.27 |
| 504.52 | 5.77 | 5.77 |
| 531.53 | 5.54 | 5.54 |
| 486.53 | 5.63 | 5.63 |
| 530.50 | 6.17 | 6.17 |
| 572.52 | 6.79 | 6.79 |
| 506.52 | 5.67 | 5.67 |
| 492.53 | 6.23 | 6.23 |