Basic Information
ID: ALA4406998
Type: Functional
Description: Protection against TNFalpha/Z-VAD-fmk-induced C57BL/6J mouse model of systemic inflammatory response syndrome assessed as increase in body temperature at 5 to 50 mg/kg, po administered via gavage 2 hrs prior to Z-VAD-fmk addition for 15 mins followed by TNFalpha stimulation for 1 hr and subsequent Z-VAD-fmk addition meaured up to 50 hrs post TNFalpha stimulation by electric thermometer
Format: BAO_0000218
Organism: Mus musculus
Strain: C57BL/6J
Target: Mus musculus(ALA375)
Document: ALA4406794
Protection against TNFalpha/Z-VAD-fmk-induced C57BL/6J mouse model of systemic inflammatory response syndrome assessed as increase in body temperature at 5 to 50 mg/kg, po administered via gavage 2 hrs prior to Z-VAD-fmk addition for 15 mins followed by TNFalpha stimulation for 1 hr and subsequent Z-VAD-fmk addition meaured up to 50 hrs post TNFalpha stimulation by electric thermometer: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4406998
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 554.53 | 6.65 | 6.65 |
| 541.40 | 6.98 | 6.98 |
| 529.52 | 6.78 | 6.78 |