Basic Information
ID: ALA4407126
Type: Binding
Description: Antagonist activity at PAR4 in human washed platelets assessed as inhibition of gamma-thrombin-induced platelet aggregation preincubated for 5 mins followed by gamma-thrombin addition and measured every 50 secs for up to 15 mins starting from 10 secs post gamma-thrombin addition in presence of recombinant hirudin
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4407126
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 287.37 | 3.93 | 3.93 |
| 301.33 | 3.22 | 3.22 |
| 331.35 | 3.23 | 3.23 |
| 285.33 | 3.60 | 3.60 |
| 255.30 | 3.51 | 3.51 |
| 269.33 | 3.77 | 3.77 |
| 281.34 | 4.08 | 4.08 |
| 270.32 | 3.25 | 3.25 |
| 301.33 | 3.22 | 3.22 |
| 331.35 | 3.23 | 3.23 |
| 301.33 | 3.22 | 3.22 |
| 331.35 | 3.23 | 3.23 |
| 377.43 | 4.79 | 4.79 |
| 407.45 | 4.80 | 4.80 |
| 513.58 | 6.38 | 6.38 |
| 377.43 | 4.79 | 4.79 |
| 271.30 | 3.21 | 3.21 |
| 349.44 | 5.36 | 5.36 |
| 301.33 | 3.22 | 3.22 |
| 301.40 | 4.32 | 4.32 |
| 319.37 | 2.61 | 2.61 |
| 299.36 | 3.99 | 3.99 |