Basic Information
ID: ALA4407127
Type: Functional
Description: Antagonist activity at full-length human PAR4 expressed in HEK293 cells assessed as inhibition of AYPGKF-induced intracellular calcium mobilization preincubated for 30 mins followed by AYPGKF addition and measured by calcium indicator-based FLIPR assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4407127
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 287.37 | 3.93 | 3.93 |
| 301.33 | 3.22 | 3.22 |
| 331.35 | 3.23 | 3.23 |
| 285.33 | 3.60 | 3.60 |
| 255.30 | 3.51 | 3.51 |
| 269.33 | 3.77 | 3.77 |
| 281.34 | 4.08 | 4.08 |
| 270.32 | 3.25 | 3.25 |
| 301.33 | 3.22 | 3.22 |
| 331.35 | 3.23 | 3.23 |
| 301.33 | 3.22 | 3.22 |
| 331.35 | 3.23 | 3.23 |
| 377.43 | 4.79 | 4.79 |
| 407.45 | 4.80 | 4.80 |
| 513.58 | 6.38 | 6.38 |
| 377.43 | 4.79 | 4.79 |
| 271.30 | 3.21 | 3.21 |
| 349.44 | 5.36 | 5.36 |
| 301.33 | 3.22 | 3.22 |
| 511.60 | 6.59 | 6.59 |
| 301.40 | 4.32 | 4.32 |
| 437.48 | 4.81 | 4.81 |
| 513.58 | 6.38 | 6.38 |
| 421.48 | 5.11 | 5.11 |
| 475.45 | 5.82 | 5.82 |
| 441.90 | 5.45 | 5.45 |
| 432.46 | 4.67 | 4.67 |
| 421.48 | 4.84 | 4.84 |
| 437.48 | 4.81 | 4.81 |
| 499.55 | 6.59 | 6.59 |
| 515.62 | 6.95 | 6.95 |
| 513.58 | 6.38 | 6.38 |
| 319.37 | 2.61 | 2.61 |
| 441.90 | 5.45 | 5.45 |
| 475.45 | 5.82 | 5.82 |
| 423.45 | 4.51 | 4.51 |
| 475.45 | 5.82 | 5.82 |
| 513.58 | 6.38 | 6.38 |
| 437.48 | 4.29 | 4.29 |
| 441.90 | 5.45 | 5.45 |
| 437.48 | 4.81 | 4.81 |
| 437.48 | 4.68 | 4.68 |
| 299.36 | 3.99 | 3.99 |
| 451.50 | 4.82 | 4.82 |