Basic Information
ID: ALA4407132
Type: Binding
Description: Antagonist activity at PAR4 in human platelet rich plasma assessed as inhibition of gamma-thrombin-induced platelet aggregation preincubated for 5 mins followed by gamma-thrombin addition and measured in presence of recombinant hirudin
Organism: Homo sapiens
Tissue: Plasma
Activity Charts
Bioactivity
Activity Types for Assay ALA4407132
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 301.33 | 3.22 | 3.22 |
| 331.35 | 3.23 | 3.23 |
| 301.33 | 3.22 | 3.22 |
| 331.35 | 3.23 | 3.23 |
| 301.33 | 3.22 | 3.22 |
| 331.35 | 3.23 | 3.23 |
| 377.43 | 4.79 | 4.79 |
| 407.45 | 4.80 | 4.80 |
| 513.58 | 6.38 | 6.38 |
| 377.43 | 4.79 | 4.79 |
| 271.30 | 3.21 | 3.21 |
| 301.33 | 3.22 | 3.22 |
| 511.60 | 6.59 | 6.59 |
| 437.48 | 4.81 | 4.81 |
| 513.58 | 6.38 | 6.38 |
| 421.48 | 5.11 | 5.11 |
| 475.45 | 5.82 | 5.82 |
| 441.90 | 5.45 | 5.45 |
| 432.46 | 4.67 | 4.67 |
| 421.48 | 4.84 | 4.84 |
| 437.48 | 4.81 | 4.81 |
| 499.55 | 6.59 | 6.59 |
| 515.62 | 6.95 | 6.95 |
| 513.58 | 6.38 | 6.38 |
| 441.90 | 5.45 | 5.45 |
| 475.45 | 5.82 | 5.82 |
| 423.45 | 4.51 | 4.51 |
| 475.45 | 5.82 | 5.82 |
| 513.58 | 6.38 | 6.38 |
| 437.48 | 4.29 | 4.29 |
| 441.90 | 5.45 | 5.45 |
| 437.48 | 4.81 | 4.81 |
| 437.48 | 4.68 | 4.68 |
| 451.50 | 4.82 | 4.82 |