Basic Information
ID: ALA4407318
Type: Functional
Description: Antagonist activity at human 5HT2B receptor expressed in Flp-In-HEK cells co-expressing Gq assessed as inhibition of 5HT-induced stimulation of calcium mobilization preincubated for 10 mins followed by 5HT addition by fluo-4 calcium dye-based FLIPR assay
Format: BAO_0000219
Organism: Homo sapiens
Target: Serotonin 2b (5-HT2b) receptor(ALA1833)
Document: ALA4406806
Antagonist activity at human 5HT2B receptor expressed in Flp-In-HEK cells co-expressing Gq assessed as inhibition of 5HT-induced stimulation of calcium mobilization preincubated for 10 mins followed by 5HT addition by fluo-4 calcium dye-based FLIPR assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4407318
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 417.44 | 4.16 | 4.16 |
| 369.86 | 3.31 | 3.31 |
| 355.83 | 2.92 | 2.92 |