Basic Information
ID: ALA4407537
Type: Functional
Description: Inverse agonist activity at human A1AR expressed in CHO cells assessed as increase in forskolin-stimulated cAMP production by alphascreen assay relative to DPCPX
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CHO
Target: Adenosine A1 receptor(ALA226)
Document: ALA4406810
Inverse agonist activity at human A1AR expressed in CHO cells assessed as increase in forskolin-stimulated cAMP production by alphascreen assay relative to DPCPX: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4407537
Emax
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 390.42 | 3.50 | 3.50 |
| 333.38 | 3.35 | 3.35 |
| 333.38 | 3.35 | 3.35 |
| 390.42 | 3.75 | 3.75 |
| 297.34 | 1.55 | 1.55 |
| 302.38 | 2.22 | 2.22 |
| 286.32 | 1.75 | 1.75 |
| 406.49 | 4.21 | 4.21 |
| 357.40 | 3.83 | 3.83 |
| 401.45 | 3.55 | 3.55 |
| 380.39 | 3.34 | 3.34 |
| 362.41 | 3.45 | 3.45 |
| 360.40 | 3.64 | 3.64 |
| 390.42 | 3.75 | 3.75 |
| 286.32 | 1.75 | 1.75 |
| 375.41 | 3.06 | 3.06 |
| 376.40 | 3.66 | 3.66 |
| 302.38 | 2.22 | 2.22 |