Assay Report Card

Basic Information

ID: ALA4407573

Type: ADME

Description: Inhibition of recombinant human GST-tagged EGFR cytoplasmic domain (668 to 1210 residues) expressed in baculovirus expression system at 25 uM using FRET-labeled tyr 04 peptide as substrate measured after 1 hr by Z'-lyte assay relative to control

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
395.063.383.38
429.923.383.38
424.943.363.36