Basic Information
ID: ALA4407713
Type: Binding
Description: Inhibition of TNF-alpha induced NFkappaB in human IB31 cells assessed as reduction in IL-8 mRNA expression preincubated for 5 hrs followed by TNF-alpha stimulation measured after 24 hrs by RT-qPCR analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4407713
MIC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 242.27 | 3.72 | 3.72 |
| 270.33 | 4.36 | 4.36 |
| 256.30 | 4.28 | 4.28 |
| 256.30 | 4.11 | 4.11 |
| 256.30 | 3.97 | 3.97 |
| 242.27 | 3.72 | 3.72 |
| 270.33 | 4.53 | 4.53 |
| 242.27 | 3.77 | 3.77 |
| 228.25 | 3.46 | 3.46 |
| 244.25 | 2.65 | 2.65 |
| 229.24 | 2.31 | 2.31 |
| 242.27 | 3.77 | 3.77 |
| 228.25 | 3.46 | 3.46 |