Basic Information
ID: ALA4408250
Type: Binding
Description: Positive allosteric modulation of recombinant human GluN1/GluN2B receptor stably expressed in HEK293 cells assessed as increase in glycine/L-glutamate-induced channel current at -70 mV holding potential by IonWork two-electrode voltage clamp method
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4408250
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 402.66 | 6.36 | 6.36 |
| 402.66 | 6.50 | 6.50 |
| 402.66 | 6.36 | 6.36 |
| 388.64 | 6.11 | 6.11 |
| 360.58 | 5.33 | 5.33 |
| 388.64 | 6.26 | 6.26 |
| 374.61 | 5.72 | 5.72 |
| 402.66 | 6.50 | 6.50 |
| 402.66 | 6.50 | 6.50 |
| 374.61 | 5.72 | 5.72 |
| 386.62 | 5.87 | 5.87 |
| 402.66 | 6.50 | 6.50 |
| 442.61 | 6.66 | 6.66 |
| 402.66 | 6.50 | 6.50 |
| 414.67 | 6.50 | 6.50 |
| 416.69 | 6.75 | 6.75 |
| 400.65 | 6.26 | 6.26 |
| 416.69 | 7.16 | 7.16 |
| 388.64 | 6.11 | 6.11 |
| 428.70 | 6.89 | 6.89 |
| 402.66 | 6.50 | 6.50 |
| 428.70 | 6.89 | 6.89 |
| 442.61 | 6.66 | 6.66 |
| 414.67 | 6.50 | 6.50 |
| 388.64 | 6.11 | 6.11 |
| 360.58 | 5.33 | 5.33 |
| 416.69 | 6.75 | 6.75 |