Basic Information
ID: ALA4408336
Type: Binding
Description: Inhibition of recombinant Mycobacterium tuberculosis H37Rv ICL1 expressed in Escherichia coli BL21 (DE3) cells at 10 uM using (+)-potassium Ds-threo-isocitrate as substrate by glyoxylate phenyl hydrazone formation assay relative to control
Format: BAO_0000219
Organism: Mycobacterium tuberculosis H37Rv
Target: Unchecked(ALA612545)
Document: ALA4406824
Inhibition of recombinant Mycobacterium tuberculosis H37Rv ICL1 expressed in Escherichia coli BL21 (DE3) cells at 10 uM using (+)-potassium Ds-threo-isocitrate as substrate by glyoxylate phenyl hydrazone formation assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4408336
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 137.14 | -0.31 | -0.31 |
| 153.14 | 0.67 | 0.67 |
| 119.08 | -0.26 | -0.26 |
| 275.74 | 3.67 | 3.67 |
| 451.75 | 5.78 | 5.78 |
| 459.37 | 6.30 | 6.30 |
| 429.30 | 5.58 | 5.58 |
| 415.28 | 5.53 | 5.53 |
| 401.25 | 5.86 | 5.86 |
| 407.30 | 5.67 | 5.67 |
| 473.75 | 5.69 | 5.69 |
| 503.82 | 6.41 | 6.41 |
| 390.84 | 5.15 | 5.15 |
| 384.79 | 5.34 | 5.34 |
| 398.82 | 5.02 | 5.02 |
| 412.85 | 5.06 | 5.06 |
| 338.41 | 4.36 | 4.36 |
| 332.36 | 4.55 | 4.55 |
| 346.39 | 4.23 | 4.23 |
| 360.41 | 4.27 | 4.27 |
| 459.73 | 5.64 | 5.64 |
| 445.70 | 5.97 | 5.97 |
| 390.48 | 5.00 | 5.00 |
| 247.68 | 3.95 | 3.95 |
| 434.80 | 6.22 | 6.22 |
| 462.86 | 5.94 | 5.94 |
| 442.92 | 5.79 | 5.79 |
| 261.71 | 3.63 | 3.63 |
| 492.93 | 6.67 | 6.67 |
| 448.83 | 5.90 | 5.90 |
| 253.73 | 3.76 | 3.76 |
| 440.85 | 6.03 | 6.03 |
| 305.80 | 4.40 | 4.40 |