Basic Information
ID: ALA4408339
Type: ADME
Description: Cytostatic activity against human HepG2 cells preincubated for overnight in serum free medium followed by compound wash out and further incubated for 72 hrs in presence of serum by MTT assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HepG2
Target: HepG2(ALA395)
Document: ALA4406824
Cytostatic activity against human HepG2 cells preincubated for overnight in serum free medium followed by compound wash out and further incubated for 72 hrs in presence of serum by MTT assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4408339
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 137.14 | -0.31 | -0.31 |
| 153.14 | 0.67 | 0.67 |
| 275.74 | 3.67 | 3.67 |
| 451.75 | 5.78 | 5.78 |
| 459.37 | 6.30 | 6.30 |
| 429.30 | 5.58 | 5.58 |
| 415.28 | 5.53 | 5.53 |
| 401.25 | 5.86 | 5.86 |
| 407.30 | 5.67 | 5.67 |
| 473.75 | 5.69 | 5.69 |
| 503.82 | 6.41 | 6.41 |
| 390.84 | 5.15 | 5.15 |
| 384.79 | 5.34 | 5.34 |
| 398.82 | 5.02 | 5.02 |
| 412.85 | 5.06 | 5.06 |
| 338.41 | 4.36 | 4.36 |
| 332.36 | 4.55 | 4.55 |
| 346.39 | 4.23 | 4.23 |
| 360.41 | 4.27 | 4.27 |
| 459.73 | 5.64 | 5.64 |
| 445.70 | 5.97 | 5.97 |
| 390.48 | 5.00 | 5.00 |
| 247.68 | 3.95 | 3.95 |
| 434.80 | 6.22 | 6.22 |
| 462.86 | 5.94 | 5.94 |
| 442.92 | 5.79 | 5.79 |
| 261.71 | 3.63 | 3.63 |
| 492.93 | 6.67 | 6.67 |
| 448.83 | 5.90 | 5.90 |
| 253.73 | 3.76 | 3.76 |
| 440.85 | 6.03 | 6.03 |
| 305.80 | 4.40 | 4.40 |