Basic Information
ID: ALA4408437
Type: Binding
Description: Inhibition of steroid sulfatase in human JEG3 cell lysates assessed as residual activity at 10 uM using [3H] E1S as substrate after 20 hr by scintillation spectrometry analysis relative to control
Format: BAO_0000220
Organism: Homo sapiens
Subcellular Fraction: Lysate
Target: Steryl-sulfatase(ALA3559)
Document: ALA4406829
Inhibition of steroid sulfatase in human JEG3 cell lysates assessed as residual activity at 10 uM using [3H] E1S as substrate after 20 hr by scintillation spectrometry analysis relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4408437
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 390.47 | 1.62 | 1.62 |
| 376.44 | 1.62 | 1.62 |
| 394.43 | 1.76 | 1.76 |
| 410.88 | 2.28 | 2.28 |
| 390.47 | 1.93 | 1.93 |
| 404.49 | 2.24 | 2.24 |
| 406.46 | 1.63 | 1.63 |
| 406.46 | 1.63 | 1.63 |
| 494.53 | 2.83 | 2.83 |
| 522.51 | 3.10 | 3.10 |
| 514.56 | 2.10 | 2.10 |
| 468.54 | 2.39 | 2.39 |
| 438.94 | 2.89 | 2.89 |
| 445.33 | 2.93 | 2.93 |
| 390.47 | 1.93 | 1.93 |
| 428.87 | 2.42 | 2.42 |
| 458.60 | 3.70 | 3.70 |
| 430.49 | 2.36 | 2.36 |
| 440.61 | 3.56 | 3.56 |
| 475.06 | 4.21 | 4.21 |
| 430.55 | 2.92 | 2.92 |
| 544.59 | 2.11 | 2.11 |
| 447.00 | 3.43 | 3.43 |
| 458.60 | 3.70 | 3.70 |
| 475.06 | 4.21 | 4.21 |
| 533.41 | 2.84 | 2.84 |
| 454.51 | 2.08 | 2.08 |
| 447.00 | 3.43 | 3.43 |
| 422.48 | 2.38 | 2.38 |
| 430.55 | 2.92 | 2.92 |
| 412.56 | 2.78 | 2.78 |
| 428.87 | 2.42 | 2.42 |
| 484.54 | 2.09 | 2.09 |
| 398.53 | 2.39 | 2.39 |
| 445.33 | 2.93 | 2.93 |