Basic Information
ID: ALA4408455
Type: Binding
Description: Inhibition of full length human FASN transfected in HeLa cell lysates at 10 uM using acetyl Co-A/malonyl Co-A as substrate preincubated with enzyme for 2 hrs followed by substrate addition measured after 10 mins in presence of NADPH by microplate reader analysis
Format: BAO_0000220
Organism: Homo sapiens
Cell type: HeLa
Subcellular Fraction: Lysate
Target: Fatty acid synthase(ALA4158)
Document: ALA4406830
Inhibition of full length human FASN transfected in HeLa cell lysates at 10 uM using acetyl Co-A/malonyl Co-A as substrate preincubated with enzyme for 2 hrs followed by substrate addition measured after 10 mins in presence of NADPH by microplate reader analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4408455
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 458.38 | 2.23 | 2.23 |
| 516.46 | 4.53 | 4.53 |
| 600.62 | 6.35 | 6.35 |
| 516.46 | 4.53 | 4.53 |