Basic Information
ID: ALA4408484
Type: Binding
Description: Inhibition of FASN in human PC9 cells harboring FASN expression and EGFR delE746-A750 mutant assessed as disruption of AKT/FASN positive feedback loop by measuring decrease in FASN expression at 2 uM after 48 hrs by Western immunoblot based densitometric assay relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4408484
Ratio
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 516.46 | 4.53 | 4.53 |
| 516.46 | 4.53 | 4.53 |