Assay Report Card

Basic Information

ID: ALA4408485

Type: Binding

Description: Inhibition of FASN in human PC9 cells harboring FASN expression and EGFR delE746-A750 mutant assessed as disruption of AKT/FASN positive feedback loop by measuring FASN expression at 2 uM after 48 hrs in presence of exogenous lipid concentrate by Western immunoblot based densitometric assay relative to control

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
516.464.534.53
516.464.534.53