Basic Information
ID: ALA4408505
Type: Binding
Description: Agonist activity at human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as peak current amplitude at -90 mV holding potential by two-electrode voltage clamp method relative to acetylcholine
Format: BAO_0000219
Organism: Homo sapiens
Target: Neuronal acetylcholine receptor protein alpha-7 subunit(ALA2492)
Document: ALA4406831
Agonist activity at human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as peak current amplitude at -90 mV holding potential by two-electrode voltage clamp method relative to acetylcholine: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4408505
Emax
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 320.85 | 3.38 | 3.38 |
| 396.49 | 3.98 | 3.98 |
| 337.40 | 3.06 | 3.06 |
| 443.52 | 4.63 | 4.63 |
| 349.43 | 2.93 | 2.93 |
| 319.41 | 2.92 | 2.92 |
| 335.41 | 2.62 | 2.62 |
| 391.52 | 3.95 | 3.95 |
| 410.52 | 4.29 | 4.29 |
| 273.38 | 1.65 | 1.65 |
| 402.54 | 3.91 | 3.91 |
| 388.52 | 3.52 | 3.52 |
| 395.51 | 4.58 | 4.58 |
| 377.49 | 3.70 | 3.70 |
| 405.54 | 4.48 | 4.48 |
| 353.85 | 3.57 | 3.57 |
| 409.53 | 4.89 | 4.89 |
| 387.41 | 3.94 | 3.94 |
| 333.44 | 3.22 | 3.22 |
| 413.50 | 4.72 | 4.72 |
| 373.46 | 2.93 | 2.93 |
| 359.47 | 3.79 | 3.79 |
| 377.49 | 3.71 | 3.71 |
| 401.54 | 4.65 | 4.65 |
| 396.49 | 3.98 | 3.98 |
| 398.30 | 3.68 | 3.68 |
| 426.52 | 3.89 | 3.89 |
| 385.41 | 3.52 | 3.52 |
| 375.47 | 3.48 | 3.48 |
| 451.61 | 5.88 | 5.88 |
| 389.50 | 3.85 | 3.85 |
| 405.54 | 4.48 | 4.48 |
| 425.53 | 4.50 | 4.50 |
| 259.35 | 1.26 | 1.26 |