Basic Information
ID: ALA4408862
Type: Binding
Description: Transactivation of FXR (unknown origin) transfected in HepG2 cells co-expressing pBSEP/pGL4.74 incubated for 24 hrs by luciferase reporter gene assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HepG2
Target: Bile acid receptor FXR(ALA2047)
Document: ALA4406841
Transactivation of FXR (unknown origin) transfected in HepG2 cells co-expressing pBSEP/pGL4.74 incubated for 24 hrs by luciferase reporter gene assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4408862
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 490.73 | 4.79 | 4.79 |
| 506.72 | 4.01 | 4.01 |
| 472.71 | 5.84 | 5.84 |
| 532.76 | 5.37 | 5.37 |
| 472.71 | 5.60 | 5.60 |
| 488.71 | 4.81 | 4.81 |
| 530.75 | 5.38 | 5.38 |
| 484.68 | 4.99 | 4.99 |
| 468.68 | 5.58 | 5.58 |
| 528.73 | 5.35 | 5.35 |
| 502.69 | 4.13 | 4.13 |
| 518.78 | 5.84 | 5.84 |
| 456.71 | 6.63 | 6.63 |
| 488.71 | 4.57 | 4.57 |
| 456.71 | 6.63 | 6.63 |
| 468.68 | 5.82 | 5.82 |
| 474.68 | 4.32 | 4.32 |
| 368.52 | 4.85 | 4.85 |
| 532.76 | 5.37 | 5.37 |
| 474.73 | 5.82 | 5.82 |
| 470.69 | 5.62 | 5.62 |
| 512.73 | 6.19 | 6.19 |
| 470.69 | 5.62 | 5.62 |
| 514.75 | 5.82 | 5.82 |
| 530.75 | 5.38 | 5.38 |
| 468.68 | 5.98 | 5.98 |
| 520.71 | 2.94 | 2.94 |
| 444.70 | 6.32 | 6.32 |
| 460.66 | 5.10 | 5.10 |
| 528.73 | 5.59 | 5.59 |
| 504.71 | 3.97 | 3.97 |
| 522.72 | 2.74 | 2.74 |
| 546.79 | 5.56 | 5.56 |
| 530.75 | 5.38 | 5.38 |
| 530.75 | 5.38 | 5.38 |
| 488.71 | 4.81 | 4.81 |
| 484.72 | 6.27 | 6.27 |
| 512.78 | 7.40 | 7.40 |
| 516.76 | 6.39 | 6.39 |
| 504.71 | 3.97 | 3.97 |
| 486.69 | 4.78 | 4.78 |
| 544.77 | 6.04 | 6.04 |
| 526.76 | 6.58 | 6.58 |
| 546.83 | 6.62 | 6.62 |
| 470.69 | 5.62 | 5.62 |
| 502.74 | 7.58 | 7.58 |
| 446.67 | 5.92 | 5.92 |
| 528.73 | 6.20 | 6.20 |
| 472.71 | 5.89 | 5.89 |
| 560.82 | 5.81 | 5.81 |
| 518.78 | 6.31 | 6.31 |
| 562.79 | 4.99 | 4.99 |
| 502.74 | 5.47 | 5.47 |
| 502.69 | 4.13 | 4.13 |
| 504.71 | 3.97 | 3.97 |
| 504.75 | 5.45 | 5.45 |
| 514.75 | 6.41 | 6.41 |
| 440.67 | 6.45 | 6.45 |
| 506.72 | 3.77 | 3.77 |
| 530.75 | 5.38 | 5.38 |
| 558.80 | 6.43 | 6.43 |
| 514.75 | 6.41 | 6.41 |
| 488.71 | 4.81 | 4.81 |
| 470.69 | 5.86 | 5.86 |
| 456.71 | 6.63 | 6.63 |
| 412.57 | 5.05 | 5.05 |
| 456.71 | 6.87 | 6.87 |
| 472.71 | 5.84 | 5.84 |
| 412.57 | 5.05 | 5.05 |