Basic Information
ID: ALA4409187
Type: Toxicity
Description: Selectivity ratio of IC50 for inhibition of recombinant Cryptosporidium hominis TS-DHFR expresssed in Escherichia coli PA414 to IC50 for inhibition of recombinant human His6-tagged TS
Activity Charts
Bioactivity
Activity Types for Assay ALA4409187
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 433.42 | 1.87 | 1.87 |
| 409.45 | 1.80 | 1.80 |
| 427.43 | 1.86 | 1.86 |
| 447.45 | 2.31 | 2.31 |
| 417.43 | 2.30 | 2.30 |
| 447.45 | 2.52 | 2.52 |
| 461.43 | 2.00 | 2.00 |
| 446.42 | 1.47 | 1.47 |
| 433.42 | 2.38 | 2.38 |
| 447.45 | 2.52 | 2.52 |
| 431.45 | 2.69 | 2.69 |
| 403.40 | 2.37 | 2.37 |
| 433.42 | 2.38 | 2.38 |
| 403.40 | 2.37 | 2.37 |
| 403.40 | 2.37 | 2.37 |
| 386.41 | 3.29 | 3.29 |
| 447.41 | 2.07 | 2.07 |
| 428.41 | 2.25 | 2.25 |
| 390.40 | 2.80 | 2.80 |
| 417.43 | 2.05 | 2.05 |
| 384.40 | 2.55 | 2.55 |
| 442.44 | 2.18 | 2.18 |
| 395.42 | 1.50 | 1.50 |
| 437.84 | 3.03 | 3.03 |