Basic Information
ID: ALA4409452
Type: Binding
Description: Inhibition of recombinant human N-terminal GST-tagged ALK L1196M mutant (1058 to 1620 residues) expressed in baculovirus expression system using Srctide as substrate incubated with enzyme and substrate for 5 mins followed by ATP addition followed by further incubation for 30 mins by HTRF assay
Format: BAO_0000019
Organism: Homo sapiens
Target: ALK tyrosine kinase receptor(ALA4247)
Document: ALA4406858
Inhibition of recombinant human N-terminal GST-tagged ALK L1196M mutant (1058 to 1620 residues) expressed in baculovirus expression system using Srctide as substrate incubated with enzyme and substrate for 5 mins followed by ATP addition followed by further incubation for 30 mins by HTRF assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4409452
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 450.35 | 5.04 | 5.04 |
| 394.23 | 4.61 | 4.61 |
| 422.29 | 5.10 | 5.10 |
| 484.36 | 6.13 | 6.13 |
| 465.36 | 4.64 | 4.64 |
| 408.26 | 4.62 | 4.62 |