Basic Information
ID: ALA4409554
Type: Binding
Description: Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells assessed as reduction in kynurenine production using L-tryptophan as substrate incubated for 24 hrs
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HeLa
Target: Indoleamine 2,3-dioxygenase(ALA4685)
Document: ALA4406863
Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells assessed as reduction in kynurenine production using L-tryptophan as substrate incubated for 24 hrs: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4409554
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 320.35 | 3.32 | 3.32 |
| 305.34 | 3.70 | 3.70 |
| 427.48 | 2.47 | 2.47 |
| 349.39 | 3.12 | 3.12 |
| 438.24 | 0.42 | 0.42 |
| 282.39 | 3.78 | 3.78 |
| 367.88 | 4.82 | 4.82 |
| 399.86 | 3.69 | 3.69 |
| 353.43 | 3.70 | 3.70 |
| 285.30 | 1.13 | 1.13 |
| 269.33 | 3.45 | 3.45 |
| 404.45 | 3.47 | 3.47 |
| 425.51 | 5.23 | 5.23 |
| 430.33 | 4.02 | 4.02 |
| 369.88 | 4.21 | 4.21 |
| 468.38 | 4.51 | 4.51 |
| 349.35 | 3.15 | 3.15 |
| 348.40 | 3.69 | 3.69 |
| 370.86 | 4.44 | 4.44 |
| 395.89 | 4.85 | 4.85 |
| 334.38 | 3.71 | 3.71 |
| 349.35 | 3.15 | 3.15 |
| 513.00 | 5.19 | 5.19 |
| 347.45 | 3.20 | 3.20 |
| 334.38 | 3.25 | 3.25 |
| 333.39 | 3.38 | 3.38 |
| 401.34 | 3.65 | 3.65 |
| 381.46 | 3.27 | 3.27 |
| 394.89 | 4.00 | 4.00 |
| 436.47 | 3.29 | 3.29 |
| 371.49 | 3.71 | 3.71 |
| 430.47 | 2.00 | 2.00 |
| 405.48 | 4.08 | 4.08 |
| 379.89 | 5.14 | 5.14 |
| 383.41 | 3.12 | 3.12 |
| 451.50 | 3.79 | 3.79 |
| 452.54 | 6.16 | 6.16 |