Basic Information
ID: ALA4409560
Type: Binding
Description: Reversal of IDO1-mediated immunosuppression in mouse CT26 co-cultured with T-cells assessed as ConA- stimulated differentiation of Treg cells at 0.3 uM measured after 48 hrs by FOXP3-APC based flow cytometry analysis (Rvb = 11.4 %)
Format: BAO_0000019
Organism: Mus musculus
Target: Indoleamine 2,3-dioxygenase 1(ALA1075294)
Document: ALA4406863
Reversal of IDO1-mediated immunosuppression in mouse CT26 co-cultured with T-cells assessed as ConA- stimulated differentiation of Treg cells at 0.3 uM measured after 48 hrs by FOXP3-APC based flow cytometry analysis (Rvb = 11.4 %): 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4409560
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 395.89 | 4.85 | 4.85 |
| 329.83 | 3.99 | 3.99 |
| 405.48 | 4.08 | 4.08 |