Basic Information
ID: ALA4410460
Type: ADME
Description: Half life in human liver microsomes at 1 uM preincubated for 5 mins followed by NADPH addition and measured for 45 mins by LC/MS analysis
Format: BAO_0000251
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Target: ADMET(ALA612558)
Document: ALA4406888
Half life in human liver microsomes at 1 uM preincubated for 5 mins followed by NADPH addition and measured for 45 mins by LC/MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4410460
T1/2
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 395.43 | 2.42 | 2.42 |
| 358.40 | 3.88 | 3.88 |
| 361.38 | 4.19 | 4.19 |
| 362.36 | 4.24 | 4.24 |
| 348.36 | 3.48 | 3.48 |
| 358.40 | 3.88 | 3.88 |
| 336.40 | 3.48 | 3.48 |
| 362.36 | 4.24 | 4.24 |
| 349.37 | 4.23 | 4.23 |
| 359.39 | 3.28 | 3.28 |
| 344.37 | 4.10 | 4.10 |
| 331.38 | 4.09 | 4.09 |
| 376.39 | 4.02 | 4.02 |