Basic Information
ID: ALA4410608
Type: Binding
Description: Ratio of compound Ki to pyrimethamine Ki for competitive inhibition of wild type Plasmodium falciparum dihydrofolate reductase expressed in Escherichia coli BL21(DE3)pLysS using dihydrofolate as substrate
Organism: Plasmodium falciparum
Activity Charts
Bioactivity
Activity Types for Assay ALA4410608
Ratio Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 214.27 | 1.87 | 1.87 |
| 248.72 | 2.52 | 2.52 |
| 419.36 | 4.75 | 4.75 |
| 430.89 | 3.13 | 3.13 |
| 491.42 | 4.47 | 4.47 |
| 479.36 | 3.83 | 3.83 |
| 430.89 | 2.78 | 2.78 |
| 495.45 | 5.76 | 5.76 |
| 402.84 | 2.35 | 2.35 |
| 467.40 | 5.33 | 5.33 |
| 493.39 | 4.22 | 4.22 |
| 507.42 | 4.61 | 4.61 |
| 384.91 | 4.10 | 4.10 |
| 465.34 | 3.78 | 3.78 |
| 432.96 | 4.67 | 4.67 |
| 370.88 | 3.71 | 3.71 |
| 456.97 | 3.82 | 3.82 |
| 472.97 | 3.95 | 3.95 |
| 356.86 | 3.32 | 3.32 |
| 461.01 | 5.10 | 5.10 |
| 405.33 | 4.36 | 4.36 |
| 391.30 | 3.97 | 3.97 |
| 437.28 | 3.00 | 3.00 |
| 458.95 | 3.56 | 3.56 |
| 444.92 | 3.17 | 3.17 |
| 465.34 | 3.44 | 3.44 |