Assay Report Card

Basic Information

ID: ALA4410613

Type: Toxicity

Description: Selectivity ratio of Ki for human dihydrofolate reductase to Ki for wild type Plasmodium falciparum TM4/8.2 dihydrofolate reductase

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
248.722.522.52
214.271.871.87
248.722.522.52
419.364.754.75
430.893.133.13
491.424.474.47
479.363.833.83
430.892.782.78
495.455.765.76
402.842.352.35
467.405.335.33
493.394.224.22
507.424.614.61
384.914.104.10
465.343.783.78
432.964.674.67
370.883.713.71
456.973.823.82
472.973.953.95
356.863.323.32
461.015.105.10
405.334.364.36
391.303.973.97
437.283.003.00
458.953.563.56
444.923.173.17
465.343.443.44