Basic Information
ID: ALA4410741
Type: Functional
Description: Antiallergic activity in rat RBL2H3 cells assessed as inhibition of C48/80-induced mast cell degranulation preincubated with compound for 30 mins and then treated with C48/80 for 1 hr by neutral red dye based method
Format: BAO_0000219
Organism: Rattus norvegicus
Cell type: RBL-2H3
Target: RBL-2H3(ALA614632)
Document: ALA4406904
Antiallergic activity in rat RBL2H3 cells assessed as inhibition of C48/80-induced mast cell degranulation preincubated with compound for 30 mins and then treated with C48/80 for 1 hr by neutral red dye based method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4410741
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 274.80 | 3.82 | 3.82 |
| 285.39 | 2.66 | 2.66 |
| 458.58 | 5.35 | 5.35 |
| 284.40 | 3.26 | 3.26 |
| 332.88 | 3.96 | 3.96 |
| 299.42 | 2.97 | 2.97 |
| 300.41 | 2.24 | 2.24 |
| 333.86 | 3.35 | 3.35 |
| 313.45 | 2.89 | 2.89 |
| 319.84 | 3.31 | 3.31 |
| 312.46 | 3.61 | 3.61 |
| 314.43 | 2.28 | 2.28 |
| 299.42 | 2.85 | 2.85 |
| 299.42 | 2.70 | 2.70 |
| 298.43 | 3.31 | 3.31 |
| 313.45 | 3.01 | 3.01 |
| 298.43 | 3.57 | 3.57 |
| 318.85 | 3.92 | 3.92 |