Basic Information
ID: ALA4410849
Type: Binding
Description: Inhibition of IDO1 in human whole blood stimulated with IFNgamma/LPS assessed as unbound potency using L-tryptophan/kynurenine as substrate incubated for 15 mins followed by IFNgamma/LPS stimulation and incubated for 18 hrs by LC/MS-MS analysis
Organism: Homo sapiens
Tissue: Blood
Activity Charts
Bioactivity
Activity Types for Assay ALA4410849
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 320.28 | 0.13 | 0.13 |
| 381.39 | 0.43 | 0.43 |
| 263.23 | 0.81 | 0.81 |
| 364.34 | -0.25 | -0.25 |
| 385.38 | -0.56 | -0.56 |
| 402.43 | 0.12 | 0.12 |
| 365.39 | 1.46 | 1.46 |