Basic Information
ID: ALA4410888
Type: Binding
Description: Inhibition of human N-terminal GST-tagged EGFR triple T790M/L858R/C797S mutant (696 to 1022 residues) expressed in Sf21 insect cells by HTRF assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Sf21
Target: Epidermal growth factor receptor erbB1(ALA203)
Document: ALA4406912
Inhibition of human N-terminal GST-tagged EGFR triple T790M/L858R/C797S mutant (696 to 1022 residues) expressed in Sf21 insect cells by HTRF assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4410888
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 383.40 | 3.32 | 3.32 |
| 318.35 | 4.73 | 4.73 |
| 494.57 | 5.93 | 5.93 |
| 478.57 | 5.81 | 5.81 |
| 508.60 | 6.27 | 6.27 |