Basic Information
ID: ALA4410890
Type: Binding
Description: Inhibition of EGFR L858R mutant (unknown origin) expressed in mouse Ba/F3 cells assessed as reduction in cell growth incubated for 72 hrs in presence of 1 ug/ml Cetuximab by celltiter-glo luminescent cell viability assay
Format: BAO_0000219
Organism: Homo sapiens
Target: Epidermal growth factor receptor erbB1(ALA203)
Document: ALA4406912
Inhibition of EGFR L858R mutant (unknown origin) expressed in mouse Ba/F3 cells assessed as reduction in cell growth incubated for 72 hrs in presence of 1 ug/ml Cetuximab by celltiter-glo luminescent cell viability assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4410890
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 383.40 | 3.32 | 3.32 |
| 318.35 | 4.73 | 4.73 |
| 494.57 | 5.93 | 5.93 |
| 478.57 | 5.81 | 5.81 |
| 508.60 | 6.27 | 6.27 |