Basic Information
ID: ALA4411113
Type: Binding
Description: Inhibition of recombinant porcine brain PREP expressed in Escherichia coli assessed as formation of 7-amido-4-methylcoumarin using Suc-Gly-Pro-amido-4-methylcoumarin as substrate preincubated for 30 mins followed by substrate addition measured after 60 mins by fluorometric assay
Organism: Sus scrofa
Activity Charts
Bioactivity
Activity Types for Assay ALA4411113
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 314.43 | 2.62 | 2.62 |
| 339.44 | 2.51 | 2.51 |
| 382.47 | 1.88 | 1.88 |
| 370.46 | 1.73 | 1.73 |
| 299.37 | 1.64 | 1.64 |
| 327.43 | 2.37 | 2.37 |
| 332.40 | 1.59 | 1.59 |
| 342.40 | 1.00 | 1.00 |
| 357.45 | 1.48 | 1.48 |
| 356.43 | 1.34 | 1.34 |
| 356.43 | 1.39 | 1.39 |
| 288.39 | 2.14 | 2.14 |
| 313.40 | 1.98 | 1.98 |
| 313.40 | 2.03 | 2.03 |
| 358.44 | 2.08 | 2.08 |