Basic Information
ID: ALA4411114
Type: Binding
Description: Inhibition of PREP in C57BL/6 mouse cortex homogenate assessed as formation of 7-amido-4-methylcoumarin using Suc-Gly-Pro-amido-4-methylcoumarin as substrate preincubated for 30 mins followed by substrate addition measured after 60 mins by fluorometric assay
Organism: Mus musculus
Strain: C57BL/6
Activity Charts
Bioactivity
Activity Types for Assay ALA4411114
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 339.44 | 2.51 | 2.51 |
| 331.42 | 0.94 | 0.94 |
| 317.39 | 0.60 | 0.60 |
| 299.37 | 1.64 | 1.64 |
| 345.44 | 1.33 | 1.33 |
| 302.42 | 2.53 | 2.53 |
| 356.43 | 1.39 | 1.39 |
| 288.39 | 2.09 | 2.09 |
| 313.40 | 2.03 | 2.03 |
| 288.39 | 2.14 | 2.14 |
| 302.42 | 2.48 | 2.48 |
| 288.39 | 2.14 | 2.14 |
| 331.42 | 0.99 | 0.99 |