Basic Information
ID: ALA4411121
Type: Binding
Description: Antagonist activity at human recombinant mu opioid receptor expressed in CHO-K1 cell membranes assessed as intrinsic activity at 10 pM to 20 uM incubated for 30 mins in presence of Eu-GTP by DELFIA GTP binding assay relative to DAMGO
Organism: Homo sapiens
Cell type: CHO-K1
Activity Charts
Bioactivity
Activity Types for Assay ALA4411121
Intrinsic activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 341.41 | 1.53 | 1.53 |
| 323.48 | 4.62 | 4.62 |
| 436.35 | 1.67 | 1.67 |
| 555.69 | 2.26 | 2.26 |
| 421.54 | 2.52 | 2.52 |
| 463.57 | 3.14 | 3.14 |
| 489.68 | 2.95 | 2.95 |
| 427.59 | 2.90 | 2.90 |
| 435.57 | 2.56 | 2.56 |
| 449.60 | 2.95 | 2.95 |
| 454.66 | 4.50 | 4.50 |
| 413.56 | 2.51 | 2.51 |
| 399.54 | 2.12 | 2.12 |
| 476.69 | 3.18 | 3.18 |
| 367.49 | 3.94 | 3.94 |
| 479.63 | 2.66 | 2.66 |
| 429.61 | 3.14 | 3.14 |
| 277.36 | 2.47 | 2.47 |
| 411.59 | 3.92 | 3.92 |
| 415.58 | 2.75 | 2.75 |
| 463.62 | 4.81 | 4.81 |
| 369.55 | 3.67 | 3.67 |
| 447.65 | 3.34 | 3.34 |
| 471.69 | 4.31 | 4.31 |
| 457.66 | 3.92 | 3.92 |
| 427.59 | 4.14 | 4.14 |
| 443.63 | 3.53 | 3.53 |
| 465.56 | 4.47 | 4.47 |
| 453.67 | 4.95 | 4.95 |
| 415.58 | 2.90 | 2.90 |
| 410.51 | 2.88 | 2.88 |
| 429.56 | 1.74 | 1.74 |