Basic Information
ID: ALA4411173
Type: Binding
Description: Inhibition of DOT1L in human HeLa cells assessed as reduction in H3K79 dimethylation measured after 72 hrs by ELISA
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HeLa
Target: Histone-lysine N-methyltransferase, H3 lysine-79 specific(ALA1795117)
Document: ALA4406923
Inhibition of DOT1L in human HeLa cells assessed as reduction in H3K79 dimethylation measured after 72 hrs by ELISA: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4411173
ED50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 592.97 | 3.42 | 3.42 |
| 526.98 | 4.11 | 4.11 |
| 562.99 | 4.56 | 4.56 |
| 607.00 | 4.61 | 4.61 |