Basic Information
ID: ALA4411174
Type: Binding
Description: Inhibition of DOT1L in human MOLM13 cells assessed as reduction in HOXA9 gene expression incubated for 72 hrs by bright-glo luciferase reporter gene assay
Format: BAO_0000219
Organism: Homo sapiens
Target: Histone-lysine N-methyltransferase, H3 lysine-79 specific(ALA1795117)
Document: ALA4406923
Inhibition of DOT1L in human MOLM13 cells assessed as reduction in HOXA9 gene expression incubated for 72 hrs by bright-glo luciferase reporter gene assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4411174
ED50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 592.97 | 3.42 | 3.42 |
| 526.98 | 4.11 | 4.11 |
| 607.00 | 4.61 | 4.61 |