ID: ALA4411225
Type: Binding
Description: Inhibition of human MB-COMT expressed in HEK293 cells using dopamine as substrate and SAM as cofactor preincubated for 30 mins followed by substrate addition and measured after 40 mins by HTRF assay
Organism: Homo sapiens
Cell type: HEK293
Bioactivity
Activity Types for Assay ALA4411225
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
273.24 | 2.55 | 2.55 |
256.31 | 1.57 | 1.57 |
324.30 | 2.59 | 2.59 |
222.29 | 1.03 | 1.03 |
308.74 | 2.36 | 2.36 |
166.18 | -0.34 | -0.34 |
292.29 | 1.85 | 1.85 |
290.75 | 2.22 | 2.22 |
270.33 | 1.61 | 1.61 |
284.36 | 2.19 | 2.19 |
325.19 | 2.88 | 2.88 |
284.36 | 2.19 | 2.19 |
325.19 | 2.88 | 2.88 |
270.33 | 1.88 | 1.88 |
257.29 | 0.96 | 0.96 |
286.33 | 1.58 | 1.58 |
274.30 | 1.71 | 1.71 |
288.28 | 1.35 | 1.35 |
308.74 | 2.36 | 2.36 |
286.33 | 1.58 | 1.58 |
250.34 | 1.81 | 1.81 |
324.30 | 2.59 | 2.59 |
281.31 | 1.44 | 1.44 |
306.34 | 0.76 | 0.76 |
284.36 | 2.19 | 2.19 |
284.36 | 2.19 | 2.19 |
281.31 | 1.44 | 1.44 |