Assay Report Card

Basic Information

ID: ALA4411225

Type: Binding

Description: Inhibition of human MB-COMT expressed in HEK293 cells using dopamine as substrate and SAM as cofactor preincubated for 30 mins followed by substrate addition and measured after 40 mins by HTRF assay

Organism: Homo sapiens

Cell type: HEK293

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
273.242.552.55
256.311.571.57
324.302.592.59
222.291.031.03
308.742.362.36
166.18-0.34-0.34
292.291.851.85
290.752.222.22
270.331.611.61
284.362.192.19
325.192.882.88
284.362.192.19
325.192.882.88
270.331.881.88
257.290.960.96
286.331.581.58
274.301.711.71
288.281.351.35
308.742.362.36
286.331.581.58
250.341.811.81
324.302.592.59
281.311.441.44
306.340.760.76
284.362.192.19
284.362.192.19
281.311.441.44