Basic Information
ID: ALA4411244
Type: Binding
Description: Inhibition of recombinant human C-terminal His6-tagged S-COMT expressed in 293-6E cells using 7,8-dihydroxy-4-methylcoumarin as substrate and SAM as cofactor incubated for 1 hr by MTase Glo methyltransferase assay
Format: BAO_0000219
Organism: Homo sapiens
Target: Catechol O-methyltransferase(ALA2023)
Document: ALA4406925
Inhibition of recombinant human C-terminal His6-tagged S-COMT expressed in 293-6E cells using 7,8-dihydroxy-4-methylcoumarin as substrate and SAM as cofactor incubated for 1 hr by MTase Glo methyltransferase assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4411244
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 256.31 | 1.57 | 1.57 |
| 290.75 | 2.22 | 2.22 |
| 325.19 | 2.88 | 2.88 |
| 284.36 | 2.19 | 2.19 |
| 308.74 | 2.36 | 2.36 |