In vivo inhibition of COMT in rat assessed as change in HVA level at 100 mg/kg, po measured after 4 hrs by LC-MS analysis relative to control

Basic Information

ID: ALA4411252

Type: Functional

Description: In vivo inhibition of COMT in rat assessed as change in HVA level at 100 mg/kg, po measured after 4 hrs by LC-MS analysis relative to control

Format: BAO_0000218

Organism: Rattus norvegicus

Target: Rattus norvegicus(ALA376)

Document: ALA4406925

In vivo inhibition of COMT in rat assessed as change in HVA level at 100 mg/kg, po measured after 4 hrs by LC-MS analysis relative to control: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4411252

Activity

Total(5)

Parent Molecular Weight	ALogP	Polar Surface Area
256.31	1.57	1.57
290.75	2.22	2.22
325.19	2.88	2.88
284.36	2.19	2.19
308.74	2.36	2.36

Parent Molecular Weight

ALogP

Polar Surface Area

256.31

1.57

290.75

2.22

325.19

2.88

284.36

2.19

308.74

2.36

In vivo inhibition of COMT in rat assessed as change in HVA level at 100 mg/kg, po measured after 4 hrs by LC-MS analysis relative to control

Basic Information

Activity Charts

Compound Summary