Basic Information
ID: ALA4411583
Type: Binding
Description: Inhibition of JAK1/JAK2 signaling pathway in human CD14 +ve cells of whole blood assessed as reduction in IFN-gamma induced STAT1 phosphorylation preincubated for 45 mins followed by IFN-gamma addition and measured measured after 15 mins by FACS assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4411583
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 312.38 | 1.54 | 1.54 |
| 389.41 | 1.79 | 1.79 |