Basic Information
ID: ALA4411585
Type: Binding
Description: Inhibition of JAK1/JAK2 signaling pathway in human CD3 +ve cells of whole blood assessed as reduction in IL-6 induced STAT3 phosphorylation preincubated for 45 mins followed by IL-6 addition and measured measured after 15 mins by FACS assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4411585
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 312.38 | 1.54 | 1.54 |
| 389.41 | 1.79 | 1.79 |