Basic Information
ID: ALA4411586
Type: Binding
Description: Inhibition of JAK1/TYK2 signaling pathway in human lymphocytes of whole blood assessed as reduction in IL-10 induced STAT3 phosphorylation preincubated for 45 mins followed by IL-10 addition and measured measured after 15 mins by FACS assay
Format: BAO_0000219
Organism: Homo sapiens
Target: JAK1/TYK2(ALA3301391)
Document: ALA4411260
Inhibition of JAK1/TYK2 signaling pathway in human lymphocytes of whole blood assessed as reduction in IL-10 induced STAT3 phosphorylation preincubated for 45 mins followed by IL-10 addition and measured measured after 15 mins by FACS assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4411586
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 312.38 | 1.54 | 1.54 |
| 389.41 | 1.79 | 1.79 |